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PD-Chromeo™ Nanoparticles

photostable, oxygen-resistant fluorescent particles ideal for lifetime measurements

PD-Chromeo™ Nanoparticles utilize a novel cross-linked polymer to encapsulate the high-intensity Chromeo Dyes, which enhances both their sensitivity and ease of use. PD-Chromeo Nanoparticle suspensions have a similar appearance to polystyrene-based particles, but display much lower oxygen permeability. This results in higher photostability for most dyes, making them ideal for lifetime (decay) measurements. In addition, PD-Chromeo complexes can easily be centrifuged at pH 5 and resuspended at pH 7, which further improves their use in labeling biological molecules, such as antibodies. Combined with the lipophilic forms of the Chromeo Dyes, Active Motif Chromeon PD-Chromeo Nanoparticles represent a useful tool for protein labeling and antibody-conjugation.

PD-Chromeo Nanoparticles are less than 100 nm in size; they are available with your choice of 3 different Chromeo Dyes, and can be provided either carboxylated or with surface modifications. If carboxy groups interfere with your experiments, PD-Chromeo Nanoparticles are also available with proteinic- or tensidic-blocked surfaces.

If you cannot find your desired surface in our product list, please feel free to contact our service department.

PD-Chromeo Nanoparticle Advantages

• Small size (< 100 nm)
• High density of carboxylic groups for better conjugation
• Brightness – high intensity fluorescence for improved sensitivity
• pH stable
• Photostable

PD-Chromeo Nanoparticles

Contents & Storage

All nanoparticles are supplied as a 0.5% (w/w) aqueous suspension in buffer (10 mM MES, pH 7) and are guaranteed stable for at least 6 months when stored at 4°C.